BSAVA · Saunders
This instruction has conditions or a sequence that must be read in the source context.
Complete dosage context; follow the species labels and conditions in the text.
When used for sedation is generally given as part of a combination. See Appendix for sedation protocols in cats and dogs. Dogs: Analgesia: 0.02 mg/kg i.v., i.m., s.c. q6h. Cats: Analgesia: 0.02–0.03 mg/kg i.v., i.m., s.c. q6h. Also well tolerated with some efficacy when given oral transmucosally.
This instruction has conditions or a sequence that must be read in the source context. This passage does not contain one unambiguous dose amount or interval.
Dogs
- 0.006-0.02 mg/kg q4-8h IV, IM, or SQ. For analgesia, doses have been increased to as high as 0.03-0.04 mg/kg SQ.
- Constant rate infusion (CRI): 20 mcg/kg IV, followed by 5 mcg/kg/hour infusion.
- Epidural: 0.003-0.006 mg/kg (3-6 mcg/kg).
- Buprenorphine SR: 120-270 mcg/kg (0.12-0.27 mg/kg) SQ (duration of 72 hours).
This passage does not contain one unambiguous dose amount or interval. This instruction has conditions or a sequence that must be read in the source context. An explicit supported administration route is required.
Cats
- For analgesia, a dose of 0.01-0.02 mg/kg (10-20 mcg/kg) IV or 0.02 mg/kg (20 mcg/kg) IM. Duration is 4-6 hours typically. Additional doses of 0.02 mg/kg may be administered.
- Constant rate infusion (CRI): 20 mcg/kg IV, followed by 12 mcg/kg/hour infusion.
- Subcutaneous administration: The concentrated formulation (Simbadol can be administered SQ once daily for up to 3 days at a dose of 0.24 mg/kg (240 mcg/kg). This formulation may be administered prior to surgery.
- Buccal (transmucosal) administration: 0.02-0.04 mg/kg (20-40 mcg/kg) q8h. 0.02 mg/kg (20 mcg/kg) is equivalent to 0.066 mL per kg. This may be applied to the cat's gingival or oral mucosa (i.e., sublingual).
- Epidural: 12.5 mcg/kg diluted with saline to a volume of 0.3 mL/kg.
- Buprenorphine SR: 120 mcg/kg-270 mcg/kg (0.12-0.27 mg/kg) SQ (duration of 72 hours).
This passage does not contain one unambiguous dose amount or interval.
Horses
- 0.005-0.01 mg/kg (5-10 mcg/kg IM); short acting in horses.
This passage does not contain one unambiguous dose amount or interval.
Sheep
- 0.01 mg/kg (10 mcg/kg) IM, q6h.